M S

وبلاگی گروهی در خصوص هرانچه در مورد بیماری ام اس میتوان گفت

نفرین نامه

فهرست داروهاي ام اس

تاييد شده :
1. Avonex (interferon beta 1a)
2. Betaseron (interferon beta 1b)
3. Copaxone (glatiramir acetate)
4. Novantrone (mitoxantrone)
5. Rebif (interferon beta 1a)

درمان هايي كه براي ام اس تاييد نشده اند ولي مورد استفاده قرار مي گيرند :
1. Azathioprine (aka Imuran)
2. Cyclophosphamide (aka Cytoxan)
3. Doxycycline, Amoxicillin, Rifampin, Metronidazole
4. Doxycycline, Roxithromycin, Metronidazole
5. Intravenous Immune Globulin (IVIg)
6. Low-Dose Naltrexone (aka LDN)
7. Methotrexate
8. Mycophenolate mofetil (aka Cellcept)
9. Plasma exchange (aka plasmapheresis)

فاز 3 آزمايش
1. Betaseron (500 mcg dose) (Schering)
2. BG12 (Fumapharm and Biogen)
3. Campath (aka alemtuzumab) (Genzyme)
4. FTY720 (aka fingolimod) (Novartis)
5. MBP8298 (BioMS) (trial for SPMS)
6. Mycophenolate mofetil (aka Cellcept) (with Avonex)
7. Mylinax (oral cladribine) (Serono)
8. Progestin and Estradiol (Hospices Civils de Lyon)
9. Rebif (fetal bovine serum-free/human serum albumin-free) (Serono)
10. Rituximab (aka Rituxan) (Biogen / Genentech) (primary progressive MS trial)
11. Stem cells - autologous hematopoietic (HSCT) –
سلول بنيادي
12. Teriflunomide (aka HMR 1726) (Sanofi-Aventis)
13. Tysabri (natalizumab) (Biogen / Elan)

فاز 2 آزمايش
1. ABT-874 (Abbott) (SPMS and RRMS)
2. Aimspro (suspended) (Daval)
3. Albuterol (aka Proventil) (with Copaxone)
4. Alferon N Injection
5. Alpha lipoic acid
6. ATL-1102 (Antisense Therapeutics)
7. Bacille Calmette-Guèrin (BCG) Vaccine
8. BHT-3009-01 (Bayhill Therapeutics) (with Lipitor)
9. C-6448 (Merck)
10. Chaperonin 10 (Cpn10) (C-Bio)
11. CNTO1275 (Centocor)
12. Cyclophosphamide (aka Cytoxan) (SPMS)
13. Daclizumab (aka Zenapax) (Protein Design Labs, Biogen-Idec)
14. DNA vaccination (Stanford University)
15. Doxycycline (with Avonex)
16. E2007 (Eisai)
17. Fludarabine phosphate (aka Fludara) (with Avonex)
18. GEM-SP (SPMS) (Gemacbio)
19. Inosine
20. interferon alpha (oral) (University of Texas-Houston)
21. Interferon enhancing therapy (aka EMZ701) (Transition Therapeutics)
22. Interferon-tau (aka tauferon) (Pepgen)
23. Kynurenine (aka Tranilast) (Stanford)
24. Lamotrigine (Lamictal) (Glaxosmithkline)
25. Laquinimod (aka ABR-215062) (Teva)
26. Lipitor (aka atorvastatin) (Pfizer)
27. MBP8298 (BioMS) (RRMS trial)
28. Mesopram (Berlex)
29. Minocyline (with copaxone)
30. MK-0812 (Merck)
31. MLN1202 (Millenium)
32. MN-166 (aka ibudilast and Ketas) (Medicinova)
33. N-acetyl-L-cysteine (with copaxone)
34. Neurovax (Immune Response Corp)
35. Omega 3 Fatty Acids (completed)
36. Pioglitazone (Actos)
37. Pirfenidone (aka Deskar) (Intermune) (trial for SPMS complete)
38. Pixantrone (aka BBR 2778) (Cell Therapeutics)
39. Pravastatin (Nantes University Hospital - France)
40. RO0506997 (Hoffmann-La Roche)
41. Rituximab (aka Rituxan) (Biogen / Genentech) (RRMS trial)
42. RPI-78M (Nutra Pharma / ReceptoPharm)
43. Sirolimus (aka Rapamune) (Wyeth)
44. T-Cell Vaccination (Sheba Medical Center)
45. Temsirolimus (CCI-779) (Wyeth)
46. Testosterone
47. Topiramate (aka Topamax) (with Avonex)
48. Tovaxin (Pharmafrontiers)
49. TV-5010 (Teva)
50. Xaliproden (SR 57746) (Sanofi-Aventis)
51. Zocor (aka simvastatin) (Merck)

فاز 1 آزمايش
1. AL-108 (Allon)
2. Anti-CD154
3. AZD4750 (Astra Zeneca)
4. AVE9897 (Sanofi-Aventis)
5. Cannabinor (Pharmos)
6. CCX915 (CCR2 antagonist) (ChemoCentryx)
7. CDP323 (Celltech)
8. CTLA4-Ig (Repligen)
9. DADMe-Immunicillin-H (Albert Einstein College of Medicine)
10. DW908e (Daiichi - oral)
11. Gemfibrozil (aka Lopid)
12. Genz 29155 (Genzyme)
13. JNK Inhibitor (Serono)
14. LGD5552 (Ligand Pharmaceuticals)
15. MDX1100 (Medarex)
16. MLN 3897 (Aventis)
17. MM-093 (Recombinant Human Alpha-Fetoprotein) (Merrimack)
18. MMP-12 Inhibitor (Serono)
19. NNZ-2566 (Neuren)
20. Plasma exchange (aka plasmapheresis) (completed?)
21. RG2007 (aka CTLA4-IgG4m) (Immune Tolerance Network)
22. Riluzole (ALS drug) (completed)
23. Sildenafil Citrate (aka Viagra)
24. Treosulfan (for SPMS)
25. TV-3606 (Teva)
26. Vitamin D3 (with calcium) (St. Michael's Hospital - Toronto)
27. ZK811752 (Schering)

پيش باليني
1. AEG35156 (XIAP antagonist) (Aegera)
2. Arvanil (synthetic capsaicin-anandamide hybrid)
3. AT-008 (Androclus)
4. AZD 5904 (Astrazeneca)
5. AZD 8797 (Astrazeneca)
6. Cathepsin S (Medivir)
7. CEP-701 (Johns Hopkins)
8. CHR-1103 (Chromos)
9. Ciliary neurotrophic factor (CNTF)
10. CT301
11. Erythropoietin (aka EPO)
12. ESPRIT (Exon Skipping Pre-RNA Interference Technology) (AVI BioPharma)
13. GEMS-001 (Gemacbio)
14. Glial Growth Factor 2 (aka GGF2) (Acorda)
15. Glucosamine (Thomas Jefferson University)
16. HP184 (Sanofi-Aventis)
17. LF 15-0195 (Universite Paul Sabatier, France)
18. LJP 1207 (La Jolla Pharmaceuticals)
19. Mikbeta1 (National Institutes of Health)
20. MLN0415 (Millenium / Sanofi-Aventis)
21. NAPVSIPQ (NAP) (Allon)
22. Neurodur (Ceptor)
23. Neutrazumab (C5a Receptor antagonist) (G2 Therapies)
24. OPN-101 (Opsona)
25. Osteopontin (Serono)
26. PXS25 / PXS64 (Pharmaxis)
27. PXS2076 (Pharmaxis)
28. QR-442 (Quigley)
29. RheoSwitch Therapeutic System + TriGrid Delivery System (RheoGene, Ichor Medical Systems)
30. ROB 895 (Oxypharma)
31. ShK(L5) (UC Irvine)
32. STA-5326 (Synta Pharmaceuticals)
33. sTNFR:Fc/p80 (Medical University of Lodz, Poland)
34. Symadex (imidazoacridinone) (Xanthus)
35. Syntonix Transceptor/SynFusion (inhaled interferon-beta:Fc) (Syntonix/Serono)
36. tetracyline (non-antibacterial) (Paratek)
37. TMC-2003 (Targeted Molecules Corp)
38. Vasoactive Intestinal Peptide (aka VIP)
39. Vitamin B12 (Hospital for Sick Children - Toronto)
40. 13-cis-retinoic acid (Kinemed

 

سلمان

+ نوشته شده در  یکشنبه سوم اردیبهشت 1385ساعت 11:54  توسط ......  |